通过检测铁死亡相关生化指标和电镜观察发现,敲除HCP5-132aa促进胃癌细胞发生铁死亡,回补SLC7A11/G6PD铁死亡发生受到抑制。上述结果表明HCP5-132aa作为支架蛋白维持蛋白复合物稳定,进而拮抗铁死亡参与胃癌进展。
soy and microprotein products, and many nuts and seeds. Vegetarians who eat a varied and balanced diet have been found to have no greater risk of iron-deficiency anaemia than non-vegetarians.
10月24日,南京医科大学研究团队在期刊《Advanced Science》上发表了题为“HCP5 Derived Novel Microprotein Triggers Progression of Gastric Cancer through Regulating ...