as an MMP2 substrate using the haemopexin domain of MMP2 as a bait 47. However, this method has not been widely adopted by the protease research community. Of the several approaches to targeting ...
【导读】胃癌（GC）是全球最致命的恶性肿瘤之一。尽管人们付出了巨大的努力来开发新的治疗靶点，但有效的治疗胃癌的药物仍然十分有限。10月18日，中山大学陈剑辉教授研究团队在期刊《Cell ...
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Unlocking the power of diet: How miRNAs influence health and diseaseIn lung cancer cells, curcumin treatment inhibited cell invasion by upregulating miR-98, which suppresses matrix metalloproteinase 2 (MMP2) and MMP9 pathways. Further, quercetin exhibited anti-cancer ...
同时结果中更为核心的MMP9 、MMP2 均属于MMP 家族的重要成员，抑制该家族是偏头痛的重要治疗靶点，而目前关于都梁方靶向MMP 家族治疗偏头痛的研究 ...
As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...
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