A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer's disease—increases the risk of ...

Deleting swip-10 negatively impacted on systemic levels of Cu(I), leading to deficits in mitochondrial respiration and ATP production, increased oxidative stress, and neurodegeneration. Conversely, ...

A UNIGE team has discovered the genetic programmes that allow motor neurons to retract from the spinal cord. This discovery ...

Progressive outer retinal thinning was observed. Conclusions Patients with MacTel sustain progressive inner retinal ...

STING, a protein known for antiviral signaling, also protects cells from stress by promoting autophagy and lysosome ...

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.

My main research interests are in neurodegeneration and in brain inflammation. In particular, I am interested in how systemic insults such as infection, inflammation and injury interact with, and ...

Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and ...

In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have ...

Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins.

Two new papers by a team of researchers demonstrate that evaluating microRNAs in blood can be used not only to diagnose mild cognitive impairment (MCI) but also, critically, to predict the conversion ...