We investigated synaptic plasticity in mouse OT slices by combining electrical stimulation and treatment with the appetite-promoting neuropeptide orexin, the receptors of which are highly expressed in ...
Orexin, also known as hypocretin, is a brain hormone that helps regulate sleep. A deficiency of this hormone can cause a person to develop type 1 narcolepsy. Type 1 narcolepsy, formerly known as ...
Idorsia has become the first drugmaker in the EU to claim approval for a drug for chronic insomnia in the dual orexin receptor antagonist class, ahead of rival drugs from Merck & Co and Eisai.