A new study by researchers at the Karolinska Institute and the University of Hamburg suggests liquid biopsy may revolutionize ...

In recent research published in eGastroenterology, Dr. J-Matthias Löhr and colleagues provide an in-depth review of ...

时间：2015年6月11日 来源：军事医学科学院编辑推荐：军事医学科学院全军干细胞与再生医学重点实验室、军事医学科学院华南干细胞与再生医学研究中心裴雪涛、岳文团队的最新研究首次揭示了微小分子RNA ...

Inhibition of CDK6 may prevent arteriovenous malformations in hereditary hemorrhagic telangiectasia by regulating endothelial ...

Patient enrollment in the Phase 1b hemodynamic trial remains ahead of expectation, with topline results now expected in late Q1’2025 or early ...

TβRI then phosphorylates the carboxyl terminus of the transcription factors SMAD2 and SMAD3, enabling them to form a complex with SMAD4. This Smad complex translocates to the nucleus to regulate ...

在SMAD4缺失突变的胰腺癌中，PGK1表达上调，核PGK1通过线粒体氧化磷酸化功能驱动细胞转移，而细胞质PGK1通过糖酵解酶的作用促进细胞增殖。这两项研究阐明了胰腺癌手术不获益亚群的潜在干预 ...

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...

SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance. Clin Cancer Res. 2019 Mar 15;25(6):1948-1956. doi: 10.1158/1078-0432.CCR-18-1726.

上一章我们了解了细胞表面的受体广泛地接收信号并把信号转导到细胞质内，这一章我们将要探讨这些大部分由生长因子受体 ...

Cancer therapeutic resistance occurs as cancers develop resistance to treatments such as chemotherapy, radiotherapy and targeted therapies, through many different mechanisms. These include ...