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MN:帕金森病始于肠道再添实锤!科学家再次揭示,帕金森病相关 ...
线粒体碎片化后暴露心磷脂,激活免疫反应,导致神经退行性病变。具体而言,研究者们在帕金森病患者和粪菌移植小鼠模型的病理样本中均观察到,中脑区域的TLR4和NFkB通路活化,促使IL-1β表达和促炎免疫通路激活。同时,PD小鼠和患者的黑质区域中IL-8和 ...
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