肝细胞癌（HCC）是最常见的原发性肝癌类型，随着死亡率的增加，已成为一个严重的全球健康问题。尽管早期患者可以通过手术切除，但仍有约50%的患者需要全身治疗。虽然免疫治疗取得了快速进展，阿替利珠单抗联合贝伐珠单抗已确定是晚期HCC的治疗方案。然而，总体 ...

and show that uORF1 affects vimentin filaments and that the identified uORFs affect virus replication in neural cells.

THRAP3, STMN1, and GNA13—are overrepresented in blood cancers like acute myeloid leukemia (AML) and could prove to be novel ...

文章解读+创新点拓展，为您带来科研新体验～导读胰腺导管腺癌（PDAC）以其高死亡率和低生存率成为最致命的癌症之一。随着对肿瘤微环境（TME）及其在癌症进展中作用理解的深入，科学家们正在探索针对癌症相关成纤维细胞（CAF）的新治疗策略。一项发表在ACS ...

Objective: To investigate the expression and activity of four isotypes of PAD in peripheral blood and synovial fluid cells of patients with RA. Conclusion: PAD2 and PAD4 are the most likely candidate ...

1 State Key Laboratory Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, College of ...

The Laboratory of Translational Virology is dedicated to improving understanding of pathogenesis and treatment of high-risk and high-consequence viral pathogens. Our laboratory aims to understand the ...

1 Department of Rheumatology and Immunology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, China 2 Department of Geriatric Medicine, The Second Affiliated Hospital of Wannan Medical ...

Specimens were routinely processed and stained with H&E. Immunohistochemical stains for CD34, CD68, vimentin, S100, smooth muscle actin (SMA), myosin, desmin, actin, Bcl-2 and Ki-67 were performed.