HLA-B27 positivity is possibly associated with severity of ankylosis. We studied the in vitro and in vivo impact of HLA-B27 in models of chondrogenesis and osteogenesis. Conclusion HLA-B27 seems to ...

Background: While several risk factors for knee osteoarthritis (KOA) have been recognized, the pathogenesis of KOA and the causal relationship between modifiable risk factors and KOA in genetic ...

90. Reeck JC, Hardy MJ, Pu X, Keller-Peck C, Oxford JT. Authentication of a novel antibody to zebrafish collagen type XI alpha 1 chain (Col11a1a). BMC Res Notes. 2021 Sep 15;14(1):359. doi: ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Wnt signaling is an important target for ...

Finally, our motif analysis additionally revealed that a number of these human height variants may alter the binding of transcription factors with important roles in chondrogenesis and gene regulatory ...

Based on the AFK-PD-promoted chondrocyte diffirentiation per se, we wondered whether AFK-PD promotes the chondrogenesis of mesenchymal stem cell (MSC). This is particularly important if AFK-PD ...

Osteoarthritis (OA) is the most common arthritis worldwide, causing pain, disability, and loss of function due to chronic joint ...

Correspondence to Dr Shunwu Fan, Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine & Key Laboratory of Musculoskeletal System Degeneration and ...