第一波是通过外胚层(epiblast)细胞中的己胺生物合成途径(hexosamine biosynthetic pathway, HBP)输送葡萄糖,促进成纤维细胞生长因子(FGF)信号传导所 ...
SEVERAL investigators have observed 1–3 that amniotic fluid contains specific components of a glycoprotein nature, which do not usually occur in human or animal sera and body fluids. In the ...
UDP-GlcNAc acts as a donor sugar and is generated through the hexosamine biosynthetic pathway, a nutrient-sensing pathway. Intracellular pools of the donor sugar UDP-GlcNAc are themselves ...
Like many cancer cells, AML cells need more sugar to grow. The hexosamine biosynthetic pathway (HBP), which is triggered by increased sugar consumption, generates a chemical essential for ...
The first wave channels glucose through the hexosamine biosynthetic pathway (HBP) in epiblast cells, facilitating the formation of proteoglycans for fibroblast growth factor (FGF) signaling.
Numerous processes and substances have been implicated in promoting atherosclerosis in conditions of hyperglycemia, including polyol pathway, protein kinase C, the formation of AGE, hexosamine ...