The first wave channels glucose through the hexosamine biosynthetic pathway (HBP) in epiblast cells, facilitating the formation of proteoglycans for fibroblast growth factor (FGF) signaling.

This manuscript reports on the crystal structures of two glycosaminoglycan (GAG) lyases from the PL35 family, along with in vitro enzyme activity assays and comprehensive structure-guided mutagenesis.

SEVERAL investigators have observed 1–3 that amniotic fluid contains specific components of a glycoprotein nature, which do not usually occur in human or animal sera and body fluids. In the ...