Background: Airway mucus hypersecretion (AMH) can occur in children with acute respiratory diseases, but its underlying mechanisms and relationship with the lower respiratory tract microbiota (LRTM) ...

The Spanish COPD guidelines recommend treatment of the mixed COPD–asthma phenotype with ICS and a long-acting bronchodilator (LABD) as a first option to improve lung function, respiratory ...

The bioavailability of pantoprazole when administered as a suspension in sodium bicarbonate solution and as the oral tablet was studied. In an open-label, randomized, two-period crossover study ...

Sparrow Pharmaceuticals, a clinical-stage biopharmaceutical company developing novel, targeted therapies to address unmet needs in both endocrinology and immunology, today announced that the Phase 2 ...

The long-term effects of asthma can undermine your quality of life and ability to participate in everyday activities. If poorly controlled, asthma can cause structural changes to the lungs, leading to ...

Objective: To describe clinical characteristics of hospitalized children with acute asthma attacks complicated with mucus plugs and to investigate the factors associated with mucus plugs in asthma ...

Patients who are unresponsive to 4–8 weeks' treatment with PPIs twice daily might have so-called refractory GERD. The first investigation these patients should undergo is upper endoscopy to ...

Neuroendocrine tumors (NETs) arise from neurosecretory cells and can affect various organs, causing diverse symptoms. They may metastasize even when small and might be hormone-secreting or non ...

Hypercortisolism can have variable clinical presentations; low-grade disease may not present with classic signs such as facial plethora, striae, or proximal myopathy. Cushing disease is the most ...