The two key methods for drug delivery in non-clinical studies are intratracheal and inhalation dosing. Intratracheal dosing – principally used for early screening studies – involves ...
Am J Health Syst Pharm. 2008;65(15):1413-1418. Anthony Sebba, M.D., is Assistant Clinical Professor, University of South Florida, 36338 U.S. Highway 19 North, Palm ...
In June 2024, Belgium-based EXO Biologics completed dosing the first cohort of its phase 1/2 EVENEW study to assess the safety and efficacy of intratracheal administered therapeutic EXOB-001 an ...
Riehl et al. administrated bleomycin intratracheally, while we administered bleomycin via an oropharyngeal route. Intratracheal instillation induces a bronchocentric PF pattern, whereas oropharyngeal ...
Peng et al. (2013) showed that bleomycin is a model substance which induces pulmonary fibrosis in mice. Based on histopathological findings, the authors described the progression of fibrosis in three ...
Institute of Analytical Chemistry and Instrument for Life Science, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an ...
Florida International University, Center for Translational Science, Port St. Lucie, Florida 34987, United States Florida International University, Robert Stempel College of Public Health and Social ...