T-cell therapy is a revolutionary immunotherapy approach in which T cells are genetically modified to express a receptor that ...

At this point, the patient developed new slurred speech and later catatonia. In this case report, we discuss the factors that could determine which patients are at risk of neurotoxicity following ...

Initial Clinical Data from Phase 1 Autoimmunity Study of FT819 1XX CAR T-cell Product Candidate to be Presented in 4Q24; ...

Tacrolimus is widely used for immunosuppression in liver transplantation; its use is however associated with neurotoxicity. Tacrolimus-associated neurotoxicity is heterogeneous in presentation and may ...

Detailed price information for Legend Biotech Corp ADR (LEGN-Q) from The Globe and Mail including charting and trades.

Lead exposure is a risk to any human, but children are most vulnerable to the element's neurotoxicity, which can lead to ...

Aucatzyl is the first CAR-T cell therapy approved by the FDA with no requirement for a risk evaluation mitigation strategy ...

The CAR-T cell therapy Carvykti has been shown to be effective among patients outside the confines of a clinical trial.

The CAR-T cell therapy Aucatzyl was approved for relapsed or refractory B-cell precursor acute lymphoblastic leukemia based ...

One key point is the favorable safety profile of Aucatzyl, which shows lower rates of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) compared to ...

Like other CAR-T products, Aucatzyl still comes with an FDA boxed warning for CRS, neurotoxicity and secondary T-cell malignancies. A lack of REMS requirement could work to further support adoption by ...