The ontogenesis of myeloid malignancies is based on complex genetic alterations and biological mechanisms. Abnormal maturation and differentiation arrest are key pathogenetic phenomena implicated in ...

5G). In this study, informed by ontogenesis and recent reports modeling PSC differentiation in vitro, we successfully differentiated human iPSCs to syndetome-like cells in a stepwise manner using a ...

The application of sophisticated molecular biology tools has unveiled a plethora of (epi)genomic and transcriptomic alterations, some of which have been recently recognized in pre-leukemic conditions ...

Life cycle and main morphological changes of the ctenophore Mnemiopsis leidyi. (A) Life cycle of the ctenophore M. leidyi. Ordinary downstream development (normal ontogenesis, clockwise) and ...

The present study was designed to evaluate the genetic mechanisms in patients with focal epileptiform discharges in the mid-temporal or central regions, an electroencephalographic abnormality of ...

They were not only essential for evolution, but they are also important during ontogenesis, and while some of them can temporarily act as pathogens, likely many more are either neutral or may actually ...