Researchers analyzed whole-genome sequencing data from 76,805 patients to identify variants in 4 genes that are associated ...

According to 2018 guidelines for Crohn's disease, anti-TNF therapy—including Humira, Remicade (infliximab), or Cimzia (certolizumab pegol—is most often used for moderate or severe disease that is ...

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a FDA = Food and Drug Administration; CYP2C9 = cytochrome P-450 isoenzyme 2C9; VKORC1 = vitamin K epoxide reductase complex subunit 1; UGT1A1 = uridine diphosphate-glucuronosyltransferase 1A1 ...

Asacol (mesalamine) and anti-TNF drugs may also contribute to a worsening of heart failure. Thiopurines such as Azasan (azathioprine) are immunosuppressive medications and can increase the risk of ...

The patient sample included 774 cases in a total of 346 individuals. For the analysis of the outcome of clinical response to thiopurines, 5 exclusion criteria were applied: exclusion of patients who ...

Background: Regulatory T (Treg) cells is required to dampen immune responses against intestinal microbiota, which aid in a healthy body to promise that the resident gut microbiota should not attract ...

Ubrogepant and rimegepant: signal detection using spontaneous reports of adverse events from the Food and Drug Administration Adverse Event Reporting System. Sodium-glucose cotransporter-2 ...