2019年3月24日，南京医科大学组织学与胚胎学系&麦吉尔大学钙研究实验室)在Aging Cell(中科院一区 IF=8)期刊上在线发表题为"1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of ...

The second step happens in the kidneys, where 25(OH)D is converted into its active form, calcitriol (1,25-dihydroxyvitamin D). Both steps rely heavily on the presence of magnesium as a cofactor.

Vitamin D functions as a soluble steroid hormone synthesized from 7-dehydrocholesterol upon exposure to ultraviolet B (UVB) radiation in the skin, and it can also be obtained from dietary sources.