San Francisco 49ers star tight end George Kittle missed his second straight practice on Friday as ESPN insider Adam Schefter ...

San Francisco 49ers starting center Jake Brendel has the worst pass-blocking grade in the NFL through two weeks, according to ...

Brock Purdy has faced the Vikings twice in his career. In both games, he turned the ball over twice, led the 49ers to just 17 ...

The San Francisco 49ers (1-1) are the favorites -- expected to win by at least a field goal, but less than a touchdown ...

Like for many other head coaches and offensive coordinators across the NFL facing the Los Angeles Rams, life has gotten a lot easier on San Francisco 49ers head ...

The San Francisco 49ers are officially listing tight end George Kittle as doubtful to play for their Week 3 divisional ...

Injuries are piling up for the 49ers as they gear up for a critical showdown against the Rams. Head coach Kyle Shanahan ...

Kyle Shanahan is considered one of the smartest offensive coaches in the NFL, but according to former NFL coach Jay Gruden, ...

If Ward is unable to go, all signs point to rookie second-round pick Renardo Green getting the start as the 49ers’ nickel ...

Following a thrashing of the UCLA Bruins last weekend, the Indiana Hoosiers (3-0) step outside of the Big Ten for a Saturday ...

Tight end George Kittle is doubtful for Sunday’s game against the Los Angeles Rams, another blow for the vaunted San Francisco 49ers’ offensive weaponry. Kittle missed practices Thursday and Friday ...

As the San Francisco 49ers prepare for what promises to be a tough season, all eyes are on safety Talanoa Hufanga. After ...