Mass spectrometry reveals protein acetylation to be as widespread as phosphorylation. Many of the acetylation sites discovered by Choudhary et al. 2 were on proteins in multisubunit complexes.
Nevertheless, this study shows that targeting fungal histone acetylation using nicotinamide — which is well tolerated in humans — or future fungal sirtuin inhibitors is a novel strategy to ...
By analyzing histone modifications, researchers have mapped a detailed chromatin structure model that governs the ripening process, emphasizing the critical role of histone acetylation in ...
It is a preferred venue for the latest research reports and reviews of epigenetics, iRNA mechanics, histone acetylation, nitric oxide signaling, eicosanoid biochemistry, angiogenesis, tumor ...
Key findings include the discovery of active genic states enriched with acetylation marks like H3K9/K14ac and H3K27ac, which are associated with genes involved in anthocyanin accumulation ...