A research team, delving into the impact of excessive prenatal prednisone exposure (PPE) on fetal development, discovered ...

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical ...

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal ...

Epigenetics regulates gene expression through modifications, impacting health and disease. Aberrant patterns can lead to ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Post-translational modifications (PTMs) of α-synuclein (α-syn) such as acetylation and phosphorylation play important yet distinct roles in regulating α-syn conformation, membrane binding, and amyloid ...

Key findings include the discovery of active genic states enriched with acetylation marks like H3K9/K14ac and H3K27ac, which are associated with genes involved in anthocyanin accumulation ...

By analyzing histone modifications, researchers have mapped a detailed chromatin structure model that governs the ripening process, emphasizing the critical role of histone acetylation in ...

The findings demonstrate the essential contribution of the microtubule network to changes in cell shape driven by mechanical forces. Furthermore, we observed a flow-dependent increase in microtubule ...

GlobalData’s report assesses the drugs in the Double Homeobox Protein 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.