Pacritinib，商品名为Vonjo，是一种用于治疗骨髓纤维化的抗癌药物。它是一种大环蛋白激酶抑制剂。它主要抑制Janus 激酶 2 (JAK2) 和Fms 样酪氨酸激酶 3\CD135 (FLT3)。

Scientists have always been fascinated by how our bodies work and how the world around us affects us. Recently, a team from ...

In general, those with variations affecting the genes – namely CYP1A2 and a gene that regulates it, called AHR – tend to ...

Introduction: Inflammatory factors released during severe coronavirus disease-19 (COVID-19) caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are known to influence drug exposure, but ...