So far, several markers have been suggested, some of which are preferentially analyzed by flow cytometry and include CD38 and ZAP70, two molecules that have been extensively studied in CLL.

100 000–250 000 events were analysed per sample. In addition to viability assessments, the expression of 39 cellular markers was analysed via metal ion-coupled antibodies. This antibody panel included ...

Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.

Rita Marker, a longtime advocate against assisted suicide, died Oct. 30 at the age of 83. Born in Washington state in 1940, Marker and her family settled in Steubenville, Ohio. After attending ...

Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California 90089, United States ...

FK866 potently inhibited NAMPT activity as demonstrated by reduced mucosal NAD, resulting in reduced abundances and activities of NAD-dependent enzymes including PARP1, Sirt6 and CD38, reduced nuclear ...

Upon a pre-specified, interim analysis after nine months of treatment, the company said sibeprenlimab therapy was associated with a “statistically significant and clinically meaningful” reduction, ...

Filspari was approved by the FDA on the strength of data from the pivotal PROTECT study, which showed it could reduce protein levels in the urine of IgAN patients, a surrogate marker. Prospects ...

No. 2 North Dakota State won the 2024 Dakota Marker, defeating No. 1 South Dakota State 13-9. With the win, the Bison end a five-game losing streak to the Jackrabbits. North Dakota State ...