Newly discovered mechanism helps detach and recycle parts of cellular canal membranes as needed – models developed using ...

Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A ...

【导读】免疫检查点阻断（ICB）疗法已成为多种晚期癌症的新治疗范式，但由于低响应率，其广泛的临床应用受到了阻碍。在这项研究中，团队采用了一种基于肽的、仿生的、自组装策略，制造了一种纳米颗粒TPM1，用于结合肿瘤细胞表面的PD-L1。2024年11月9 ...

Scientists from the Institute for Integrated Cell-Material Sciences at Kyoto University and the Department of Chemical ...

These membranes, composed of flexible lipid bilayers, can reshape and remodel themselves during processes like cell movement, division, and molecular trafficking. Until now, it was commonly assumed ...

Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed -- for instance in ...

Researchers developed a high-throughput microfluidics-based method to measure and analyze lipids in single living cells using ...

This takes place when molecules diffuse across the cell membrane by travelling through specific transport proteins. It occurs down a concentration gradient - molecules move from an area of high to ...

2024年9月19日，中国科学院上海药物研究所甘勇研究员、俞淼荣副研究员与浙江大学胡国庆教授团队合作在Nature Nanotechnology上在线发表了题为“Direct Cytosolic Delivery of siRNA via Cell Membrane Fusion Using Cholesterol-Enriched Exosomes“的研究论文。

Fatty acid biosynthesis is an energy-intensive biosynthetic pathway, and the production of the building blocks for membrane phospholipids is precisely regulated to match the rate of cell division.

引言细胞是生命活动的基本单位，内部的各个区域通过细胞器实现其特定功能。在这些细胞器中，过氧化物酶体（peroxisome）扮演着不可或缺的角色。自20世纪60年代被首次发现以来，过氧化物酶体的研究不断揭示其在细胞生理中的重要性【1】。它不仅在脂质代谢 ...