Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This ...

Scientists at Vilnius University have developed a novel gene silencing method using a type IV-A CRISPR system that silences ...

For cytoplasmic injections the mix will contain the guide RNA(s), DNA repair template(s), and Cas9 mRNA in nuclease-free buffer at concentrations determined by the core. For pronuclear microinjections ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

DNA is a complex molecule that consists of two strands coiled around each other to form a double helix structure. Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding ...

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA—a single-stranded molecule ...

For additional resources to assist in donor production, contact the core. It is recommended that the investigator request this service once they have a suitable donor DNA ready for microinjection. It ...

MSK researchers discovered that the innate immune system's chronic activation due to issues in the Mre11 complex can lead to ...

Efficient DNA repair mechanisms are essential for bacterial survival ... Role in Recombinational Repair and Double-Strand ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...