Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...

or nebulization (7%), or ipratropium bromide in a fixed-dose combination with albuterol (38%). Overall, exposure to anticholinergics was associated with a 29% higher risk of CVEs relative to no ...