Pyrimethamine, sulfadiazine and folinic acid should be administered to mothers whose seroconversion is suspected or confirmed to have occurred after 18 weeks of gestation, mothers with positive AF ...
Methotrexate is a folic acid antagonist. It works by inhibiting ... creatinine Repeat methotrexate if <15% decrease in ß-hCG level from day 4 Leucovorin ß-hCG level, CBC, LFTs, creatinine ...