引言肥胖是多种癌症类型的一个主要的诱因【1】。在与肥胖相关的女性癌症中，乳腺癌是导致死亡的主要原因【2-4】。既往研究表明，肥胖能够诱导乳腺肿瘤微环境（TME）的代谢改变和以脂肪为主的局部修饰从而促进癌症进展【5】。然而肥胖诱导的肿瘤微环境代谢物对乳 ...

谷胱甘肽（Glutathione, GSH）是一种重要的抗氧化剂，它在维持细胞内氧化还原平衡、参与抗氧化防御以及催化异种生物偶联和解毒反应中起着关键作用。

铁死亡（Ferroptosis）作为一种新兴的细胞死亡形式，近年来它在科研界可谓是风头正劲，成为不少科研工作者的新宠。自从2012年首次提出以来，铁死亡已经走过了12年的历程，而相关的发表论文数量也如何雨后春笋般，根据PubMed的数据显示，截至20 ...

In a recent study published in the journal Nutrients, researchers in the Republic of Korea evaluated the effects of ...

AN unusually high value for red cell reduced glutathione (GSH) was encountered while performing a glutathione stability test, using Beutler's 1 technique, on blood from a 2-year-old girl who ...

The active form of reduced glutathione (GSH) neutralizes free radicals in the body and supports the regeneration of vitamin C and E. The supplement is specially formulated with 500mg vitamin C to ...

Glutathione (GSH) is the most abundant non-protein thiol in eukaryotic cells. Together with its oxidized partner (GSSG), GSH maintains cellular redox homeostasis and regulates protein functions ...

Reduced glutathione or simply glutathione (γ-glutamylcysteinylglycine; GSH) is found in the cytosol of most cells of the body. GSH in the epithelial lining fluid (ELF) of the lower respiratory ...

细胞内存在抗氧化机制试图抑制这些氧化物的积累，其中谷胱甘肽过氧化物酶4（GPx4）是抵御铁死亡的主要防御机制之一，它是一种PL氢过氧化物酶，利用谷胱甘肽（GSH）作为辅助因子催化氧化脂质的还原【3, 4】。GSH的生成依赖于半胱氨酸的供应，而半胱氨酸 ...

This will help to establish if there are any clinical improvements from regular GSH inhalation. Glutathione synthetase Gamma-glutamyl cycle. Riboflavin-containing glutathione reductase Catalyzes ...

Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the ...

activate the antioxidant system, including glutathione (GSH), glutathione peroxidase (Gpx), glutathione-s-transferase, glutathione reductase, and catalase as well as alleviate lipid peroxidation ...