IGF-I and IGF-II are highly homologous to each other and to proinsulin. Although the IGFs and insulin have similar biological activities and receptor reactivity, IGF carrier proteins and one ...
The type 1 IGF receptor (IGF-IR) is activated by two ligands, IGF-1 and IGF-2, and by insulin at supraphysiological concentrations. It plays a significant role in the growth of normal and abnormal ...
IRS-1 effects on cells can be dissociated from the effects of the IGF-IR, IRS-2 and insulin receptor. IRS-1 is a biomarker of sensitivity of cancer cells to IGF-IR targeting. Hypothesis ...
IL-6 expression was significantly higher than control when exercised fascicles were exposed to: (1) anabolic steroid (normalised to: 18S; GAPDH; 18S & Con and GAPDH & Con); (2) IGF-1 (normalised to: ...
The Internet Governance Forum (IGF) is one of the most important fora in the field of internet policy, hosted by the United Nations, where a wide range of stakeholders engage in dialogue on an equal ...