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【前沿进展】JMCB丨应用胃类器官揭示MNNG导致肠上皮化生的病变过程 ...
N-甲基-N'-硝基-N-亚硝基胍(MNNG)是一种广泛用于多种胃病模型研究的诱导剂,其主要模拟生活环境和食物中亚硝胺类有害化学物质,然而MNNG导致胃黏膜发生GIM病变的机制尚不清楚。 既往基于人胃上皮细胞建立的二维GIM细胞模型,无法模拟胃的生理功能及不同 ...
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