10月24日,南京医科大学研究团队在期刊《Advanced Science》上发表了题为“HCP5 Derived Novel Microprotein Triggers Progression of Gastric Cancer through Regulating Ferroptosis ...
通过检测铁死亡相关生化指标和电镜观察发现,敲除HCP5-132aa促进胃癌细胞发生铁死亡,回补SLC7A11/G6PD铁死亡发生受到抑制。上述结果表明HCP5-132aa作为支架蛋白维持蛋白复合物稳定,进而拮抗铁死亡参与胃癌进展。
The microprotein in the mitochondria (green) and in the nucleus (blue) was overexpressed in human cells. The yellow and pink areas show that the signal of the microprotein overlaps with the ...
In a study of centenarians conducted in collaboration with scientists at Albert Einstein College of Medicine, the variant, affecting a mitochondrial microprotein called humanin, was found to be more ...
The variant, located in a mitochondrial microprotein dubbed SHLP2, was found to be highly protective against Parkinson's disease; individuals with this mutation are half as likely to develop the ...
soy and microprotein products, and many nuts and seeds. Vegetarians who eat a varied and balanced diet have been found to have no greater risk of iron-deficiency anaemia than non-vegetarians.