The bacterium Clostridioides difficile is named “difficult” for a reason. Originally, it was hard to grow in the lab, and, ...

Study finds underutilization of fidaxomicin, a recommended treatment for C. diff infection, despite increased use in hospitals.

Updated guidelines recommend fidaxomicin as the first-line agent for C difficile infection, but researchers found use in US ...

An mRNA vaccine that targets several aspects of C. difficile’s ability to cause severe disease prevented major symptoms and death in mice.

Citrus trees showing natural tolerance to citrus greening disease host bacteria that produce novel antimicrobials that can be ...

An experimental monoclonal antibody treatment appears to ease the digestive disorder ulcerative colitis in patients who've ...

Armed with what it sees as impressive clinical data and bolstered by long-standing ties to the Niemann-Pick disease type C ...

Researchers describe the mechanisms of how alterations in the CDK12 gene drive prostate cancer development and report on a promising degrader that targets CDK12 and a related gene to destroy tumors.

H. pylori infections occur across the world due to exposure to saliva or stool in contaminated water or food. Learn how the ...

About a third of people with schizophrenia are resistant to conventional antipsychotic treatment. The current "pharmaceutical arsenal is limited". Clinical trials for new medications are expensive ...

and practicing endocrinologist at an academic medical center in New York City. “GLP-1 medications [like Ozempic] are designed to be taken long-term,” explains Dr. McGowan. “They are chronic ...

A Detroit Medical Center hospital has begun treating patients with the first gene therapy for beta-thalassemia, a rare blood ...