该研究报告了膜联蛋白A1(Annexin A1,ANXA1)通过与MYC Binding Protein 2(MYCBP2) 竞争性结合PDZ And LIM Domain 7(PDLIM7)进而影响SMAD Family Member 4(SMAD4)泛素化蛋白酶体降解和脂肪生成进程的新机制,揭示了该通路在抗肥胖功能的潜在治疗策略,并提出ANXA1模拟肽进行抗 ...
该研究报告了膜联蛋白A1(Annexin A1,ANXA1)通过与MYC Binding Protein 2(MYCBP2)竞争性结合PDZ And LIM Domain 7(PDLIM7)进而影响SMAD Family Member 4(SMAD4)泛素化蛋白酶体降解和脂肪生成进程的新机制,揭示了该通路在抗肥胖功能的潜在治疗策略,并提出ANXA1模拟肽进行抗 ...