Tricyclic antidepressants (TCAs) are a class of drugs that have approval from the U.S. Food and Drug Administration (FDA) to treat depression. They work by increasing the levels of brain chemicals ...

Scientists still don't know exactly what causes depression. Some factors that contribute to it include: Tricyclic ...

SNRIs are often preferred for treating more severe cases of depression. Common examples include duloxetine, desvenlafaxine ...

Medically reviewed by Jay N. Yepuri, MDMedically reviewed by Jay N. Yepuri, MD In their 2021 guidelines, the American College ...

Antidepressant medications ... Abrupt withdrawal of TCAs is often associated with symptoms suggestive of a cholinergic nature—for example, dizziness, nausea, diarrhea, insomnia, and restlessness ...

Four classes of medications have been found to be effective in the treatment of panic disorder: selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), benzodiazepines ...

For example, in diabetic polyneuropathy ... which may affect the treatment adherence. Because tricyclic antidepressants and SNRIs are now an integral part in the management of chronic and ...

Dr Laurence Wainwright, a researcher at the University of Oxford's psychiatry department, told the BBC there is "evidence to suggest a link between tricyclic antidepressants, antipsychotics and ...

Imipramine hydrochloride (a tricyclic ... that is the target of the drug. For example, serotonin receptors are the targets of many neuroleptics and antidepressants. These receptors exist as ...

Wheate said there are different risks associated with different types of antidepressants. Tricyclic antidepressants are an older type, which are usually prescribed if other treatments are ineffective.

TCAs have been on the market the longest ... Moreover, some people with depression don't necessarily need antidepressants. For example, Strunk says that cognitive behavioral therapy has ...