Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

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Winning your fantasy football matchups in Week 3 will mean making the right choices on these tough position calls.

With stud wide receiver (and quasi-backup running back) Deebo Samuel Sr. out in Week 3, San Francisco will continue to lean on Mason in a divisional matchup against the Rams. It's a smash opportunity ...

Are you seeking fantasy football start/sit advice for your week’s lineups? We’ve got you covered. We have our Who Should I ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

George Kittle and Charvarius Ward both missed practice Thursday, three days shy of the 49ers’ visit to Los Angeles where they ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

An in-depth weekly look at NFL matchups and how they’ll affect your fantasy football lineup, with players you should start, ...

Injuries have caused many problems for the San Francisco 49ers this year, and now Brock Purdy has lost another offensive ...