Multiple sclerosis (MS) is characterized by chronic inflammation leading to central nervous system demyelination. Almost 90% of people with MS have relapsing-remitting MS (RRMS) or secondary ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the ...

重点推荐扫码下载《动物模型构建与行为评估》pdf痉挛是一种肌肉紧张度异常增高的状态，常见于中枢神经系统损伤或疾病患者。痉挛是与肌肉收缩增强导致运动和步态受损最常见相关的神经系统疾病。尽管小鼠模型被广泛用于研究与痉挛相关的神经病理机制，但痉挛的研究却较 ...

The recent identification of ion-channel subtypes and ion transporters on the myelinated axon has allowed the characterization of changes in their distribution and density after demyelination.

Using the experimental autoimmune encephalomyelitis (EAE) model of inflammatory demyelination, the research team found that ...

The complex relationship between possibly impaired cognitive function in patients with multiple sclerosis (MS) and fasting ...

Progressive Multifocal Leukoencephalopathy (PML) is a severe, life-threatening condition that poses a particular risk for MS ...

In a paper published in Science Bulletin, multi-omics analyses comprising of lipidomics (439 lipids), sterolomics (22 ...

Research published in the journal Glia has identified crucial links between dietary choices and the progression of multiple ...

Similarly, the therapy led to long-term reductions of severe symptoms of 91% and 100% for the smaller and larger doses, ...

4 Thus, without measurement of core body temperature, determining whether abnormal VEPs result from demyelination of the optic nerve or from other concomitant physiological factors is not possible ...

Mapping cell types in MS lesions reveals unique tissue niches and interactions, offering insights into the molecular drivers of multiple sclerosis progression.