The first wave channels glucose through the hexosamine biosynthetic pathway (HBP) in epiblast cells, facilitating the formation of proteoglycans for fibroblast growth factor (FGF) signaling.

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...

Our laboratory sits at the interface between stem cell biology and developmental neuroscience. We use pluripotent stem cells to model neurological development and disease with a specific focus on ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...