A recent study has shown that the prevalence of glomerular damage in adults with various forms of sickle cell anemia is much higher than previously thought. Guasch and colleagues investigated the ...
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SAN DIEGO — The investigational drug pegcetacoplan, a C3/C3b inhibitor, showed significant benefits in the treatment of patients with C3 glomerulopathy or primary immune complex–mediated ...
1 About C3 glomerulopathy (C3G) C3G is an ultra-rare, progressive kidney disease that initially presents mostly in children and young adults.3,4,9 Each year, approximately 1-2 people per ...
CFI deficiency can also manifest in renal conditions such as atypical hemolytic uremic syndrome, complement 3 glomerulopathy, or immune-complex membranoproliferative glomerulonephritis.