Two people have been killed and others injured in an explosion in Louisville, Kentucky, Tuesday that had prompted a shelter-in-place order.

An explosion at a chemical facility in Louisville, Kentucky Tuesday afternoon left at least 11 people hospitalized, officials confirmed. The blast occurred around 3 p.m. local time at the Givaudan Sense Colour facility, blowing out windows in the surrounding area. The public safety office called the emergency a "hazardous materials incident" on X.

A large explosion was heard in a Louisville, Kentucky, neighborhood on Tuesday afternoon, sources tell CNN affiliate WLKY News.