In the case of melanoma, this would mean destruction of melanocyte-containing tissue compartments such as the skin, brain or the eye. The current treatment populations involving heavily pretreated ...

Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...

Sabrina Gomes was diagnosed with Cushing's syndrome and a tumor in her thymus gland which has caused her skin color to change ...

Pigmentation on the skin intensifies due to various factors, yet it’s also a natural part of the skin's renewal process. So, ...

They discovered that ALX3, a transcription factor, binds to the promoter and represses MITF, a known regulator of melanocyte differentiation. To see if this newly discovered mechanism controlling ...

As hair ages, sheds and then repeatedly grows back, increasing numbers of the melanocyte stem cells become sluggish at their job. The stem cells stop roaming around the follicle and become fixed ...

It is also shown that when extracts of normal skin or of melanomata (both of which contain the melanocyte chalone) are injected for 5 days into mice or hamsters bearing large malignant melanomata ...

‘My hair is a symbol of pride’ Researchers behind the study, published in Nature, from the Universities of Sao Paulo and Harvard, believed the effects were linked to melanocyte stem ...

However, in this case, the experiments revealed something puzzling: The response differed between males and females. Initially unaware of the sex differences, the researchers sometimes observed a lot ...

Scientists have been able to link less pigmented sections of a hair strand to stressful events in a person’s life ANALYSIS | ...

The intensity of hair color depends on the density of pigment within the melanosome. Both eumelanin and pheomelanin are made from the amino acid tyrosine, using the enzyme tyrosinase. Increased ...

The hypothalamus integrates neurohormonal signaling from gut and adipose tissue. Specific hypothalamic nuclei, including the dorsomedial nucleus (DMN), paraventricular nucleus (PVN) and ...