Immune checkpoint inhibitors against the PD-1/PD-L1 interaction as therapeutics for various cancers have achieved great success. However, about 70% of patients do not respond well when receiving ...
Hematology Unit, Department of Medicine, University of Padova, Padova, Italy Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase mainly found in the focal adhesion regions of the plasma ...
Identification of potent COVID-19 main protease inhibitors by loading of favipiravir on Mg12O12 and Zn12O12 nanoclusters: an in silico strategy for COVID-19 treatment.
Background: Ovarian cancer is a highly aggressive malignancy with limited therapeutic options and a poor prognosis. Deubiquitinating enzymes (DUBs) have emerged as critical regulators of protein ...