Objective The success of treatment planning relies critically on our ability to predict the potential benefit of a therapy. In colorectal cancer (CRC), several nomograms are available to predict ...

Timely detection of oesophageal adenocarcinoma (OAC) and even more so its precursor Barrett’s oesophagus (BO) could contribute to decrease OAC incidence and mortality. An accurate, minimally-invasive ...

Objective High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm production. We aim to investigate if HFD-induced gut microbiota dysbiosis can functionally influence ...

3 Université Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, CRNH Auvergne, 63000, Clermont-Ferrand, France 4 Université Clermont Auvergne, CNRS, SIGMA Clermont, Institut Pascal, 63000, ...

2 Department of Gastroenterology, St Mark’s Hospital, Harrow, UK 3 Department of Gastroenterology, Llandough Hospital, Penarth, UK 4 Department of Gastroenterology, St James’s University Hospital, ...

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise ...

Correspondence to Dr Heng Xu, State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, Chengdu, China; xuheng81916{at}scu.edu.cn; Professor Zong-Guang Zhou; zhou767{at}163.com ...

Objective To determine whether proton pump inhibitors (PPIs) are associated with an increased risk of colorectal cancer, compared with histamine-2 receptor antagonists (H2RAs). Design The United ...

Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...

Correspondence to: K R Palmer, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK; kpalmer{at}golf5063.freeserve.co.uk “Medline” and “EMBASE” were searched to identify the evidence used in ...

Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...

Objective Developing a small animal model that accurately delineates the natural history of hepatitis B virus (HBV) infection and immunopathophysiology is necessary to clarify the mechanisms of ...